Memory Loss Donepezil Study (CLOSED)
The New York Memory & Healthy Aging Services
has completed recruitment for a FDA approved research study on the
treatment of menopause related memory loss. Over half of all
menopausal women experience these symptoms. Treatment may be
difficult in those women who choose not to go on or do not
tolerate hormone replacement.
There was a need to explore alternative non-hormonal
treatments for this problem.
Dr. Gayatri Devi who has a decade of experience in
this field headed this study. The results are pending as we go through data analyses.
Women who qualified for the study were able to avail themselves of several benefits without out-of-pocket expenses including:
A printed report of cognitive and memory
function, identifying intellectual strengths and weaknesses
A thorough neurologic evaluation
Half the women in the study received a non-hormonal drug that is being evaluated
for treatment in this condition
The data from this study is currently being analyzed and the results will be made available shortly.
For more information about what
this study entailed, you may call the New York Memory and
Healthy Aging Services at
(212) 517-6881 or visit
double-blind, placebo-controlled study on the tolerability and
efficacy of donepezil in the treatment of memory and cognitive
loss of menopause.
You are invited to
participate in a research study of the treatment of memory loss
and reduced thinking ability in menopausal women.
Women in menopause have symptoms including hot flashes,
vaginal dryness and memory loss. Between one-half and
three-quarters of menopausal women experience trouble with
memory and thinking ability, possibly due to reductions in brain
levels of estrogen and a brain chemical called acetylcholine.
Replacement treatment with the hormone estrogen treats over half
of all women with menopausal symptoms.
However, only 20% of menopausal women who have symptoms
use estrogen, partly due to concerns about side effects of the
to estrogen replacement have been found for some symptoms of
menopause, but a non-hormonal treatment for memory loss has not
yet been studied. This
study will investigate the usefulness of the non-hormonal
treatment, donepezil, as compared to a placebo, for treating
menopausal memory loss. Donepezil
is a prescription medication that raises brain levels of
acetylcholine and has been effective in the treatment of other
types of memory loss.
This study is now
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